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Rochborn CG, Marks LS, Tom F, Freedman S, Tuttle J, Gittleman M, et al. Following daily dosing, dutasteride serum concentrations achieve 65% of steady state concentration after 1 month and approximately 90% after 3 months.Dutasteride has a large volume of distribution 300 to 500 L and is highly bound to plasma proteins 99. Avodart India.. Nello studio di 4 anni per l IPB CombAT in cui non vi era alcuna biopsia prevista dal protocollo e tutte le diagnosi di cancro alla prostata erano basate su biopsie per sospetto di tumore per causa, le percentuali di cancro di punteggio Gleason 8-10 sono state n 8; 0, 5% per Avodart, n 11; 0, 7 % per tamsulosina e n 5; 0, 3% per la terapia di combinazione. Urology 2004;63:709-15.5%.. . Efficacy and safety of Dutasteride in the four year treatment of men with benign prostatic hyperplasia


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