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It is available for oral usage.. Because of isotretinoins teratogenicity, and to minimize fetal exposure, isotretinoin is approved for marketing only under a restricted distribution program, called iPLEDGE, approved by the FDA. This medication shouldnt be taken during pregnancy, since in other case it will be the reason for some defects and implications of a child. Isotretinoin proved to be effective in treating acne and the positive result remains for a long time.. .Isotretinoin. I have been putting off taking Roaccutane because of my fear of the side effects. One more name for this medication is retinoic acid Accutane.My derm has prescribed me 20mg of Roaccutane as a starting dose I am a female of slight/medium build. Isotretinoin must be prescribed by prescribers and dispensed by pharmacies registered and activated with the iPLEDGE program, and must only be dispensed to patients who are registered and meet all the requirements of iPLEDGE. I have moderate and very persistent acne 19 weeks of Tetralysal has barely made a dent in it. 10 mg Accutane. This is one more antibiotic for treating acne

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