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In a site mandated by FDA, the practicing dermatologists need to register their patients.According to the 2/16/10 issue of the Globe and Mail, Roche Canada has received 66 reports globally of severe skin reactions to isotretinoin, including several cases of Stevens Johnson Syndrome.. Roche Canada reports two of those cases resulted in death. Accutane in Canada. Similar restrictions are laid in other countries also. There are many more restrictions on the way the drug can be obtained in USA. SJS causes the outer layer of the skin to blister and separate in large sloughs from the dermis, or underlying layers of skin, similar to a severe burn.Although many people refer to the removal of Accutane from the market as a recall, the FDA determined in August 2010 that Accutane was not recalled by Roche for safety reasons. The pharmacists can give the drug only after checking the website.. There is severe restriction of getting Accutane in USA. . It is possible to get the drug in UK only by the prescription of dermatologist

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